Review





Similar Products

chromium single-cell multiome atac + gene expression  (10X Genomics)
90
10X Genomics chromium single-cell multiome atac + gene expression
Chromium Single Cell Multiome Atac + Gene Expression, supplied by 10X Genomics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/chromium single-cell multiome atac + gene expression/product/10X Genomics
Average 90 stars, based on 1 article reviews
chromium single-cell multiome atac + gene expression - by Bioz Stars, 2026-06
90/100 stars
  Buy from Supplier
gene expression omnibus database  (Biotechnology Information)
86
Biotechnology Information gene expression omnibus database
Gene Expression Omnibus Database, supplied by Biotechnology Information, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/gene expression omnibus database/product/Biotechnology Information
Average 86 stars, based on 1 article reviews
gene expression omnibus database - by Bioz Stars, 2026-06
86/100 stars
  Buy from Supplier
ncbi gene expression omnibus repository  (Biotechnology Information)
86
Biotechnology Information ncbi gene expression omnibus repository
Ncbi Gene Expression Omnibus Repository, supplied by Biotechnology Information, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ncbi gene expression omnibus repository/product/Biotechnology Information
Average 86 stars, based on 1 article reviews
ncbi gene expression omnibus repository - by Bioz Stars, 2026-06
86/100 stars
  Buy from Supplier
ncbi gene expression omnibus database  (Biotechnology Information)
86
Biotechnology Information ncbi gene expression omnibus database
Ncbi Gene Expression Omnibus Database, supplied by Biotechnology Information, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ncbi gene expression omnibus database/product/Biotechnology Information
Average 86 stars, based on 1 article reviews
ncbi gene expression omnibus database - by Bioz Stars, 2026-06
86/100 stars
  Buy from Supplier
spatial gene expression library  (Novogene)
86
Novogene spatial gene expression library
Robust <t>expression</t> of human RPE65 and RPGR transgenes in AAV-treated NHP retinas (A and D) Immunostaining of retina sections from AAV2-CAG- hRPE65 (NHP1) and AAV8-GRK1- hRPGRco (NHP2) treated areas detect both native NHP and transgene-derived human RPE65 and RPGR proteins, respectively. Control sections were taken from outside the treated blebs. GCL, ganglion cell layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer; PL, photoreceptor layer; RPE, retinal pigmented epithelium; CH, choroid. Scale bars, 20 μm. (B and E) <t>Spatial</t> transcriptomic maps of native versus human RPE65 (NHP1) and RPGR (NHP2) <t>gene</t> expression within retina sections. Red spots represent the locations of cell clusters expressing the gene of interest overlayed on the H&E-staining image. Scale bars, 0.5 mm. (C and F) scRNA-seq reveals the levels of transgene expression by each retinal cell type. Circle size represents the proportion of cells that express the transgene within each population, while color intensity represents the mean expression level per cell. AC, amacrine cells; BPC, bipolar cells; HC, horizontal cells; MG, Müller glia.
Spatial Gene Expression Library, supplied by Novogene, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/spatial gene expression library/product/Novogene
Average 86 stars, based on 1 article reviews
spatial gene expression library - by Bioz Stars, 2026-06
86/100 stars
  Buy from Supplier
chromium single cell gene expression solution  (10X Genomics)
86
10X Genomics chromium single cell gene expression solution
Robust <t>expression</t> of human RPE65 and RPGR transgenes in AAV-treated NHP retinas (A and D) Immunostaining of retina sections from AAV2-CAG- hRPE65 (NHP1) and AAV8-GRK1- hRPGRco (NHP2) treated areas detect both native NHP and transgene-derived human RPE65 and RPGR proteins, respectively. Control sections were taken from outside the treated blebs. GCL, ganglion cell layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer; PL, photoreceptor layer; RPE, retinal pigmented epithelium; CH, choroid. Scale bars, 20 μm. (B and E) <t>Spatial</t> transcriptomic maps of native versus human RPE65 (NHP1) and RPGR (NHP2) <t>gene</t> expression within retina sections. Red spots represent the locations of cell clusters expressing the gene of interest overlayed on the H&E-staining image. Scale bars, 0.5 mm. (C and F) scRNA-seq reveals the levels of transgene expression by each retinal cell type. Circle size represents the proportion of cells that express the transgene within each population, while color intensity represents the mean expression level per cell. AC, amacrine cells; BPC, bipolar cells; HC, horizontal cells; MG, Müller glia.
Chromium Single Cell Gene Expression Solution, supplied by 10X Genomics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/chromium single cell gene expression solution/product/10X Genomics
Average 86 stars, based on 1 article reviews
chromium single cell gene expression solution - by Bioz Stars, 2026-06
86/100 stars
  Buy from Supplier
gene expression omnibus geo datasets  (Biotechnology Information)
86
Biotechnology Information gene expression omnibus geo datasets
Robust <t>expression</t> of human RPE65 and RPGR transgenes in AAV-treated NHP retinas (A and D) Immunostaining of retina sections from AAV2-CAG- hRPE65 (NHP1) and AAV8-GRK1- hRPGRco (NHP2) treated areas detect both native NHP and transgene-derived human RPE65 and RPGR proteins, respectively. Control sections were taken from outside the treated blebs. GCL, ganglion cell layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer; PL, photoreceptor layer; RPE, retinal pigmented epithelium; CH, choroid. Scale bars, 20 μm. (B and E) <t>Spatial</t> transcriptomic maps of native versus human RPE65 (NHP1) and RPGR (NHP2) <t>gene</t> expression within retina sections. Red spots represent the locations of cell clusters expressing the gene of interest overlayed on the H&E-staining image. Scale bars, 0.5 mm. (C and F) scRNA-seq reveals the levels of transgene expression by each retinal cell type. Circle size represents the proportion of cells that express the transgene within each population, while color intensity represents the mean expression level per cell. AC, amacrine cells; BPC, bipolar cells; HC, horizontal cells; MG, Müller glia.
Gene Expression Omnibus Geo Datasets, supplied by Biotechnology Information, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/gene expression omnibus geo datasets/product/Biotechnology Information
Average 86 stars, based on 1 article reviews
gene expression omnibus geo datasets - by Bioz Stars, 2026-06
86/100 stars
  Buy from Supplier
gene expression omnibus geo database  (Biotechnology Information)
86
Biotechnology Information gene expression omnibus geo database
Robust <t>expression</t> of human RPE65 and RPGR transgenes in AAV-treated NHP retinas (A and D) Immunostaining of retina sections from AAV2-CAG- hRPE65 (NHP1) and AAV8-GRK1- hRPGRco (NHP2) treated areas detect both native NHP and transgene-derived human RPE65 and RPGR proteins, respectively. Control sections were taken from outside the treated blebs. GCL, ganglion cell layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer; PL, photoreceptor layer; RPE, retinal pigmented epithelium; CH, choroid. Scale bars, 20 μm. (B and E) <t>Spatial</t> transcriptomic maps of native versus human RPE65 (NHP1) and RPGR (NHP2) <t>gene</t> expression within retina sections. Red spots represent the locations of cell clusters expressing the gene of interest overlayed on the H&E-staining image. Scale bars, 0.5 mm. (C and F) scRNA-seq reveals the levels of transgene expression by each retinal cell type. Circle size represents the proportion of cells that express the transgene within each population, while color intensity represents the mean expression level per cell. AC, amacrine cells; BPC, bipolar cells; HC, horizontal cells; MG, Müller glia.
Gene Expression Omnibus Geo Database, supplied by Biotechnology Information, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/gene expression omnibus geo database/product/Biotechnology Information
Average 86 stars, based on 1 article reviews
gene expression omnibus geo database - by Bioz Stars, 2026-06
86/100 stars
  Buy from Supplier
5 gene expression gex libraries  (10X Genomics)
86
10X Genomics 5 gene expression gex libraries
Robust <t>expression</t> of human RPE65 and RPGR transgenes in AAV-treated NHP retinas (A and D) Immunostaining of retina sections from AAV2-CAG- hRPE65 (NHP1) and AAV8-GRK1- hRPGRco (NHP2) treated areas detect both native NHP and transgene-derived human RPE65 and RPGR proteins, respectively. Control sections were taken from outside the treated blebs. GCL, ganglion cell layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer; PL, photoreceptor layer; RPE, retinal pigmented epithelium; CH, choroid. Scale bars, 20 μm. (B and E) <t>Spatial</t> transcriptomic maps of native versus human RPE65 (NHP1) and RPGR (NHP2) <t>gene</t> expression within retina sections. Red spots represent the locations of cell clusters expressing the gene of interest overlayed on the H&E-staining image. Scale bars, 0.5 mm. (C and F) scRNA-seq reveals the levels of transgene expression by each retinal cell type. Circle size represents the proportion of cells that express the transgene within each population, while color intensity represents the mean expression level per cell. AC, amacrine cells; BPC, bipolar cells; HC, horizontal cells; MG, Müller glia.
5 Gene Expression Gex Libraries, supplied by 10X Genomics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/5 gene expression gex libraries/product/10X Genomics
Average 86 stars, based on 1 article reviews
5 gene expression gex libraries - by Bioz Stars, 2026-06
86/100 stars
  Buy from Supplier

Image Search Results


Robust expression of human RPE65 and RPGR transgenes in AAV-treated NHP retinas (A and D) Immunostaining of retina sections from AAV2-CAG- hRPE65 (NHP1) and AAV8-GRK1- hRPGRco (NHP2) treated areas detect both native NHP and transgene-derived human RPE65 and RPGR proteins, respectively. Control sections were taken from outside the treated blebs. GCL, ganglion cell layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer; PL, photoreceptor layer; RPE, retinal pigmented epithelium; CH, choroid. Scale bars, 20 μm. (B and E) Spatial transcriptomic maps of native versus human RPE65 (NHP1) and RPGR (NHP2) gene expression within retina sections. Red spots represent the locations of cell clusters expressing the gene of interest overlayed on the H&E-staining image. Scale bars, 0.5 mm. (C and F) scRNA-seq reveals the levels of transgene expression by each retinal cell type. Circle size represents the proportion of cells that express the transgene within each population, while color intensity represents the mean expression level per cell. AC, amacrine cells; BPC, bipolar cells; HC, horizontal cells; MG, Müller glia.

Journal: Molecular Therapy Advances

Article Title: Single-cell and spatial transcriptomic analyses of gene therapy-associated retinal inflammation in non-human primates

doi: 10.1016/j.omta.2026.201726

Figure Lengend Snippet: Robust expression of human RPE65 and RPGR transgenes in AAV-treated NHP retinas (A and D) Immunostaining of retina sections from AAV2-CAG- hRPE65 (NHP1) and AAV8-GRK1- hRPGRco (NHP2) treated areas detect both native NHP and transgene-derived human RPE65 and RPGR proteins, respectively. Control sections were taken from outside the treated blebs. GCL, ganglion cell layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer; PL, photoreceptor layer; RPE, retinal pigmented epithelium; CH, choroid. Scale bars, 20 μm. (B and E) Spatial transcriptomic maps of native versus human RPE65 (NHP1) and RPGR (NHP2) gene expression within retina sections. Red spots represent the locations of cell clusters expressing the gene of interest overlayed on the H&E-staining image. Scale bars, 0.5 mm. (C and F) scRNA-seq reveals the levels of transgene expression by each retinal cell type. Circle size represents the proportion of cells that express the transgene within each population, while color intensity represents the mean expression level per cell. AC, amacrine cells; BPC, bipolar cells; HC, horizontal cells; MG, Müller glia.

Article Snippet: Spatial gene expression library was finally constructed and sequenced with Illumina NovaSeq X Plus by Novogene.

Techniques: Expressing, Immunostaining, Derivative Assay, Control, Gene Expression, Staining

Distribution of mononuclear phagocytes after AAV gene therapy in NHPs (A and C) Spatial transcriptomic mapping of monocytic phagocytes (including microglia) over treated versus untreated retinal sections from NHP1 (A) and NHP2 (C). Red spots represent cells expressing the marker genes P2RY12 and HEXB . Scale bars, 0.5 mm. (B and D) Immunostaining for IBA1 demonstrates amoeboid-shaped monocytic phagocytes, consistent with activation. Scale bars, 20 μm.

Journal: Molecular Therapy Advances

Article Title: Single-cell and spatial transcriptomic analyses of gene therapy-associated retinal inflammation in non-human primates

doi: 10.1016/j.omta.2026.201726

Figure Lengend Snippet: Distribution of mononuclear phagocytes after AAV gene therapy in NHPs (A and C) Spatial transcriptomic mapping of monocytic phagocytes (including microglia) over treated versus untreated retinal sections from NHP1 (A) and NHP2 (C). Red spots represent cells expressing the marker genes P2RY12 and HEXB . Scale bars, 0.5 mm. (B and D) Immunostaining for IBA1 demonstrates amoeboid-shaped monocytic phagocytes, consistent with activation. Scale bars, 20 μm.

Article Snippet: Spatial gene expression library was finally constructed and sequenced with Illumina NovaSeq X Plus by Novogene.

Techniques: Expressing, Marker, Immunostaining, Activation Assay